The Mystics dropped their second game in as many nights to Western opponents, losing by 14 to the Sacramento Monarchs.
Alana Beard once again led the Mystics in scoring with 15 points, but it wasn't enough against 17 each from Sacramento's front court tandem of Nicole Powell and Yolanda Griffith.
The Mystics led 35-34 at the half, but were blown out by the Monarchs in the second.
Washington is now 9-10 and in fourth place in the East.
The fourth game of Washington's five game road trip is at 3 p.m. on Tuesday against the Los Angeles Sparks.